In Vitro Scolicidal Activity of the Sesquiterpenes Isofuranodiene, α-Bisabolol and Farnesol on Echinococcus granulosus Protoscoleces

Evaluation the scolicidal and cytotoxic effects of Froriepia subpinnataagainst protoscolex of Echinococcus granulosus in vitro

Background & Aim: Hydatidosis is one of the most important and prevalent parasitic diseases in Iran. Due to the fact that no definite and reliable treatment for this disease has been recorded so far, the aim of this study was to investigate the antiparasitic effect of Froriepia subpinnata (F. subpinnata) on the protoscolex stage of Echinococcus granulosus (E. granulosus) in vitro. Methods: F. ...

The Efficacy of Albendazole Mebendazole Combination Against Echinococcus granulosus Protoscoleces (an in vitro evaluation)

In vitro effects of nitazoxanide on Echinococcus granulosus protoscoleces and metacestodes.

OBJECTIVES Infection of humans and domestic ruminants with the larval stage (metacestode) of Echinococcus granulosus results in cystic echinococcosis (CE). The metacestode causes a space-occupying lesion in visceral organs, most commonly in the liver. Benzimidazole carbamate derivatives, such as mebendazole and albendazole, are currently used for chemotherapeutic treatment of CE. In human patie...

Scolicidal activity of Mesobuthus eupeus venom against the protoscolices of Echinococcus granulosus

Hydatidosis is an important zoonosis caused by a parasitic tapeworm, namely Echinococcus granulosus. This infection is distributed worldwide and affects the health as well as economic loss in both humans and animals. In most cases, the disease needs chemotherapy with or without surgery. Conventional drugs have some major problems, including drug complications, harmful <spa...

Strain characterization of Echinococcus granulosus protoscoleces of cattle origin using the in vitro vesicular development.

The aim of this work was to characterize the strain of protoscoleces of E. granulosus of cattle origin using the in vitro vesicular development. The in vitro development of these samples was compared to samples of sheep origin determined previously by genetic analyses as common sheep strain (G1). There were similarities between sheep and cattle samples not only in the time of microcysts formati...